Real-Time Sonography Distinguishes Between Two Types of Thyroid Conditions

Leesburg, VA, August 21, 2018—Real-time US can be helpful for differentiating diffuse thyroid disease (DTD) from normal thyroid parenchyma, according to an article in the September 2018 issue of the American Journal of Roentgenology (AJR).

Researchers led by Hye Shin Ahn, with the Chung-Ang University College of Medicine in Seoul, South Korea reported the results as part of the the first multicenter study to assess the diagnostic capability of real-time sonography (US). Previous single-center studies have shown US capable of identifying DTD when paired with a thyroid classification system.

A total of 214 patients underwent preoperative thyroid US, followed by thyroid surgery completed at one of four participating institutions between January and March 2017. An attending radiologist classified the US diagnosis as no DTD, indeterminate, suspicious for DTD or DTD.

After comparing these diagnoses to histopathologic results, the team found normal thyroid parenchyma and DTD had “statistically significant” difference in echogenicity, echotexture, size, glandular margin, vascularity and US classification. The team also determined US could accurately diagnose the two thyroid conditions.

The results of the current study show that real-time US can be helpful for accurately diagnosing DTD despite the involvement of multiple radiologists with variable levels of experience with thyroid US examinations and that a US finding of two or more DTD features has good diagnostic accuracy.


Founded in 1900, ARRS is the first and oldest radiology society in the United States, and is an international forum for progress in radiology. The Society's mission is to improve health through a community committed to advancing knowledge and skills in radiology. ARRS achieves its mission through an annual scientific and educational meeting, publication of the American Journal of Roentgenology (AJR) and InPractice magazine, topical symposia and webinars, and print and online educational materials. ARRS is located in Leesburg, VA.